Two RFLPs at the TNP1 locus.
نویسندگان
چکیده
Source/Description: The Human Transition Protein 1 gene (TNP1) probe (1) used was a 700 bp genomic DNA sequence cloned into the Smal site of pUC8 and was supplied by W.Engel. Polymorphisms: TNP1 identifies a two allele polymorphism with TaqI: Al = 9.6 kb; A2 = 8.4 kb. Frequency: Analysis of 20 unrelated individuals yielded frequencies: Al = 0.23; A2 = 0.77. Rsal in a screen of 10-20 unrelated individuals. Mendelian Inheritance: Autosomal co-dominant segregation has been demonstrated in 3 families. Source/Description: Oligonucleotide primers from sequence information of the TNP1 gene were used to amplify a 1.7 kb region encompassing the gene.
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ورودعنوان ژورنال:
- Nucleic acids research
دوره 19 24 شماره
صفحات -
تاریخ انتشار 1991